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Cerebral candidiasis in a child 1 year after leukaemia
Author(s) -
Tweddle Deborah A.,
Graham J. Clive,
Shankland Gillian S.,
Kernahan Jennifer
Publication year - 1998
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1046/j.1365-2141.1998.01023.x
Subject(s) - medicine , chemotherapy , differential diagnosis , myeloid leukaemia , presentation (obstetrics) , abscess , lesion , amphotericin b , biopsy , brain abscess , myeloid , pediatrics , brain biopsy , surgery , antifungal , pathology , dermatology
We describe an unusual case of a late presentation of a fungal brain abscess in a non‐neutropenic child 1 year after completing chemotherapy for M5 acute myeloid leukaemia (AML). Biopsy of the mass identified candidal hyphae and the patient was treated with 5 mg/kg of liposomal amphotericin B for 6 weeks. The lesion resolved completely and the child remains well 2 years later. Invasive fungal infection should be included in the differential diagnosis of unexplained symptoms in patients who have previously received intensive chemotherapy.