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Budd‐Chiari syndrome, portal vein and mesenteric vein thrombosis in a patient homozygous for factor V Leiden mutation treated by TIPS and thrombolysis
Author(s) -
Leebeek,
Laméris,
Van Buuren,
María Dolores Gomez,
Madretsma,
Sonneveld
Publication year - 1998
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1046/j.1365-2141.1998.00860.x
Subject(s) - medicine , budd–chiari syndrome , portal vein thrombosis , portal hypertension , mesenteric vein , thrombosis , thrombolysis , transjugular intrahepatic portosystemic shunt , portal venous pressure , factor v leiden , radiology , vein , surgery , gastroenterology , venous thrombosis , portal vein , cirrhosis , inferior vena cava , myocardial infarction
We present the first case of Budd‐Chiari syndrome in association with portal and mesenteric vein thrombosis in a patient homozygous for the factor V Leiden mutation. She was treated by transjugular intrahepatic portosystemic stent (TIPS) placement followed by local thrombolytic therapy. Venous outflow from the liver was established and the thrombi in the portal and mesenteric veins were lysed completely. This therapeutic approach may be used for such patients with this severe thrombotic event, who generally have a poor prognosis.