Premium
Acute myeloid leukaemia with t(8;16)(p11;p13) in a child after intrauterine X‐ray exposure
Author(s) -
Savaşan Süreyya,
Mohamed Anwar N.,
Lucas David R.,
Dugan Michael C.,
Ryan James R.,
R avindranath Yaddanapudi
Publication year - 1996
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1046/j.1365-2141.1996.02345.x
Subject(s) - myeloid leukaemia , medicine , myeloid , prenatal exposure , bone marrow , ionizing radiation , pregnancy , gestation , biology , irradiation , genetics , physics , nuclear physics
We describe t(8;16)(p11;p13) acute myeloid leukaemia (AML‐M4) in a 12‐year‐old white male with a history of prenatal X‐ray exposure. He had skin and bone involvement and some of the leukaemic blasts showed haemophagocytosis, characteristic features seen in t(8;16) AML. 20% of the reported cases of t(8;16)(p11;p13) AML are therapy‐related and this case further supports the possible role of the ionizing radiation in the development of this disorder.