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Congenital adrenal hyperplasia and acne in male patients
Author(s) -
Degitz K.,
Placzek M.,
Arnold B.,
Schmidt H.,
Plewig G.
Publication year - 2003
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2003.05369.x
Subject(s) - acne , congenital adrenal hyperplasia , androgen excess , medicine , hirsutism , androgen , hyperandrogenism , endocrinology , seborrhoeic dermatitis , glucocorticoid , cyp17a1 , dermatology , hormone , biology , obesity , polycystic ovary , insulin resistance , biochemistry , enzyme
Summary Seborrhoea is one pathogenic factor for acne. Androgens induce sebum production, and excess androgen may provoke or aggravate acne. In women an androgen disorder is frequently suspected when acne is accompanied by hirsutism or menstrual irregularities. In men acne may be the only symptom of androgen excess. We report three male acne patients in whom hormonal screening revealed irregularities of androgen metabolism suggestive of late‐onset congenital adrenal hyperplasia and who benefitted from low‐dose glucocorticoids. Disorders of androgen metabolism may influence acne not only in women, but also in men, and these patients may benefit from low‐dose glucocorticoid therapy.