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Acute haemorrhagic oedema of infancy associated with cytomegalovirus infection
Author(s) -
Kuroda K.,
Yabunami H.,
Hisanaga Y.
Publication year - 2002
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2002.05038.x
Subject(s) - medicine , cytomegalovirus , etiology , vasculitis , cytomegalovirus infection , serology , dermatology , complication , pathology , immunology , viral disease , virus , human cytomegalovirus , surgery , herpesviridae , disease , antibody
Summary Acute haemorrhagic oedema (AHO) of infancy is a cutaneous leukocytoclastic vasculitis, clinically characterized by the acute development of peripheral oedema and targetoid purpuric lesions on the face and extremities. It usually affects children younger than 2 years of age. The disorder follows a benign course usually without recurrence or long‐term complication. In most cases the origin is not clear, but underlying infections are assumed to play an aetiological role. We describe a 7‐month‐old boy whose clinical and histopathological features are typical of AHO. Serological tests clearly demonstrated a primary infection for cytomegalovirus (CMV). To our knowledge, this is the first reported case of AHO associated with CMV infection.