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A case of Sézary's syndrome associated with granulomatous lesions, myelodysplastic syndrome and transformation into CD30‐positive large‐cell pleomorphic lymphoma
Author(s) -
Carrozza P.M.,
Kempf W.,
Kazakov D.V.,
Dummer R.,
Burg G.
Publication year - 2002
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2002.04839.x
Subject(s) - mycosis fungoides , cd30 , lymphoma , medicine , pathology , large cell lymphoma , cutaneous lymphoma , t cell lymphoma , dermatology
Summary Sézary's syndrome (SS) is a leukaemic variant of mycosis fungoides, a cutaneous T‐cell lymphoma showing distinct clinical, histological, immunological, and genotypic features. We report a 10‐year follow‐up of a patient with SS exhibiting unusual features such as granulomatous skin lesions, transformation to a CD30‐positive large‐cell pleomorphic T‐cell lymphoma, and development of myelodysplastic syndrome and review the cases of SS reported in the literature with these unusual and rare complications.