Premium
Cutaneous sarcoidosis successfully treated with topical tacrolimus
Author(s) -
Katoh N.,
Mihara H.,
Yasuno H.
Publication year - 2002
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2002.04727.x
Subject(s) - sarcoidosis , tacrolimus , medicine , cutaneous sarcoidosis , dermatology , adverse effect , systemic disease , immunology , immunopathology , surgery , transplantation
Summary Sarcoidosis is a disorder characterized by macrophage‐ and T‐cell‐mediated responses to as yet unidentified infectious antigens or autoantigens. We describe a 62‐year‐old woman with a 10‐year history of orange–yellow plaques of sarcoidosis on her face. Her cutaneous lesions responded to topical tacrolimus ointment after unsuccessful treatment with topical and systemic corticosteroids. No adverse effects were noted with topical tacrolimus in this patient. We discuss the mode of action by which this immunosuppressive agent may act against sarcoidosis.