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Progressive extensive osteoma cutis associated with dysmorphic features: a new syndrome? Case report and review of the literature
Author(s) -
Davis M.D.P.,
Pittelkow M.R.,
Lindor N.M.,
Lundstrom C.E.,
Fitzpatrick L.A.
Publication year - 2002
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2002.04674.x
Subject(s) - medicine , osteoma , ossification , differential diagnosis , dermatology , pseudohypoparathyroidism , cutis , anatomy , calcinosis cutis , deformity , calcification , pathology , surgery , calcinosis , parathyroid hormone , calcium
Summary Osteoma cutis, also called cutaneous ossification, refers to the rare occurrence of bone in the skin. It may be primary, occurring in normal skin, or secondary, occurring in disrupted skin tissue. A 42‐year‐old white woman presented with long‐standing progressive primary osteoma cutis involving her head and neck, trunk and extremities. She had craniofacial dysmorphism with mid‐face hypoplasia, including saddle nose deformity, mild to moderate generalized joint hypermobility, extensive paravertebral ossification, and disc space calcification. The differential diagnosis for this entity is presented. This phenotype may be a previously undescribed syndrome.