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Malignant transformation of multiple dermal cylindromas
Author(s) -
Durani B.K.,
Kurzen H.,
Jaeckel A.,
Kuner N.,
Naeher H.,
Hartschuh W.
Publication year - 2001
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2001.04460.x
Subject(s) - scalp , axilla , medicine , cylindroma , malignant transformation , head and neck , pathology , dermatology , surgery , cancer , breast cancer
Cylindromas are benign tumours arising as small, solitary, slow‐growing nodules on the head and neck. Multiple cylindromas may form a ‘turban tumour’ in the autosomal dominant Brooke–Spiegler syndrome. We report two unusual cases of multiple cylindromas with transformation into cylindrocarcinomas. The first patient, a 63‐year‐old white woman, developed a cylindrocarcinoma on pre‐existing multiple cylindromas on her right shoulder. Eight months after resection she developed a lymph node metastasis in the right axilla. The second patient, a 68‐year‐old white woman, presented with multiple cylindromas of the scalp. One of these transformed into a cylindrocarcinoma, infiltrating the dura mater, with local recurrence 2 years after incomplete resection and postoperative radiation.