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Guillain–Barré syndrome in a child with systemic lupus erythematosus and anti‐Ro/SSA and anti‐La/SSB autoantibodies
Author(s) -
Miyagawa S.,
Nakajima M.,
Nishio K.,
Sogami J.,
Tsubakimoto A.,
Yoshioka A.,
Shirai T.
Publication year - 2000
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2000.03942.x
Subject(s) - medicine , anti nuclear antibody , autoantibody , immunology , lupus erythematosus , guillain barre syndrome , antibody , gamma globulin , dermatology , intravenous immunoglobulins
We report a 9‐year follow‐up of a girl with systemic lupus erythematosus (SLE) and probable Sjögren’s syndrome. At the age of 7 years, the patient developed a chilblain‐like eruption with features of SLE, including leucopenia, oral ulcers, positive rheumatoid and antinuclear antibodies and positive anti‐dsDNA, anti‐Ro/SSA and anti‐La/SSB antibodies. At the age of 13 years she developed Guillain–Barré syndrome, which completely resolved with aggressive treatment, including high‐dose corticosteroids and the use of plasma exchange followed by intravenous gammaglobulin.