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Paracoccidioidomycosis (South American blastomycosis) successfully treated with terbinafine: first case report
Author(s) -
Ollague J.M.,
De Zurita A.M.,
Calero G.
Publication year - 2000
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2000.03614.x
Subject(s) - terbinafine , paracoccidioidomycosis , medicine , discontinuation , blastomycosis , dermatology , surgery , trimethoprim , scrotum , mycosis , itraconazole , antifungal , antibiotics , pathology , microbiology and biotechnology , biology
We describe a 63‐year‐old man who presented with painful malodorous lesions in the perianal, perineal and scrotal regions. Following definitive diagnosis of paracoccidioidomycosis, he was treated initially with trimethoprim/sulphamethoxazole, but there was no clinical improvement. He then received terbinafine (Lamisil ® ) 250 mg twice daily for 6 months. There was rapid resolution of all lesions and complete relief of symptoms, without any associated side‐effects. The patient remains clinically well and without any evidence of infection 2 years after discontinuation of terbinafine treatment.