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Odorant inhalation affects skin barrier homeostasis in mice and humans
Author(s) -
Denda M.,
Tsuchiya T.,
Shoji K.,
Tanida M.
Publication year - 2000
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2000.03486.x
Subject(s) - sedative , skin barrier , inhalation , homeostasis , medicine , pharmacology , anesthesia , chemistry , dermatology
Previous studies have suggested that psychological stress delays cutaneous barrier recovery following acute barrier disruption, and that sedative drugs block this delay. A sedative effect of some odorants has been reported. In the present study, we demonstrate that odorant inhalation affects cutaneous barrier homeostasis in both mice and humans. Odorants with a sedative effect prevented the delay of skin barrier recovery induced by stress after acute barrier disruption. Other odorants did not show this effect.