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Cerebriform nodular amelanotic metastases of malignant melanoma: a challenge in differential diagnosis of a rare variant
Author(s) -
Assmann A.,
Farthmann B.,
Burkhardt O.,
Dippel E.,
Orfanos C.E.,
BlumePeytavi U.
Publication year - 2000
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2000.03372.x
Subject(s) - differential diagnosis , occult , medicine , melanoma , pathology , amelanotic melanoma , dermatology , alternative medicine , cancer research
High variability of the clinical appearance of malignant melanoma (MM) and its metastases render the differential diagnosis of solid amelanotic tumours difficult. We report a 71‐year‐old woman with several unusual cutaneous tumours of cerebriform morphology, suggesting skin metastases from occult internal cancer. Histopathological findings and thorough investigations, however, revealed a late‐stage metastatic MM. We discuss the differential diagnosis of skin metastases of various origin and underline the difficulties for early detection of MM.

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