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Acute arsenic poisoning: clinical and histopathological features
Author(s) -
Bartolomé B.,
Córdoba S.,
Nieto S.,
FernándezHerrera J.,
GarcíaDíez A.
Publication year - 1999
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1999.03213.x
Subject(s) - garcia , medicine , dermatology , library science , history , art , humanities , computer science
We report a woman with acute arsenic poisoning, who developed an erythroderma with vesicles and pustules after the ingestion of 8–16 g of sodium arsenite. Simultaneously, she presented a herpes simplex virus infection. Skin biopsies showed unique features which included multiple small pigment granules inside and outside the histiocytes. In our opinion, these findings are consistent with acute arsenic poisoning, and constitute the first histological description of this entity in skin.