Premium
Mycobacterium avium infection of the skin associated with lichen scrofulosorum: report of three cases
Author(s) -
Komatsu,
Terunuma,
Tabata,
Tagami
Publication year - 1999
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1999.03059.x
Subject(s) - mycobacterium avium complex , mycobacterium , dermatology , medicine , microbiology and biotechnology , mycobacterium infections , immunology , biology , pathology , tuberculosis
We report three Japanese children with Mycobacterium avium infection of the skin who also developed lichen scrofulosorum, a previously undescribed association. They were healthy except for the presence of several noduloulcerative lesions associated with multiple asymptomatic papules on the trunk and extremities. Histology of the ulcerative lesions showed features of mixed‐cell granuloma, whereas the papular lesions showed features consistent with lichen scrofulosorum. M. avium was identified by polymerase chain reaction‐aided DNA–DNA hybridization analysis in specimens obtained from the noduloulcerative lesions. Both the noduloulcerative and the papular lesions responded well to combination chemotherapy consisting of antituberculous agents and antibiotics.