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Keratotsis punctata of the palmar creases: report of two cases associated with ichthyosis vulgaris
Author(s) -
Miquel Just,
Miquel Ribera,
Isabel Bielsa,
Ana Calatrava,
Carlos Ferrándiz
Publication year - 1999
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1999.03058.x
Subject(s) - ichthyosis , ichthyosis vulgaris , dermatology , histopathology , medicine , etretinate , keratosis , hyperkeratosis , dyskeratosis , keratin , lamellar ichthyosis , pathology , psoriasis , atopic dermatitis , filaggrin
Two patients with keratosis punctata of the palmar creases are described. The association with ichthyosis vulgaris and other disorders of keratinization is discussed. In both cases, histopathology revealed a close relation between the keratotic plug and the sweat glands. The role of genetic factors and manual activity in the pathogenesis is discussed. Treatment with oral etretinate resulted in a good improvement in the first patient, but prolonged low‐dose maintenance therapy was required to prevent recurrence.