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Photodynamic therapy for inoperable vulval Paget's disease using δ‐aminolaevulinic acid: successful management of a large skin lesion
Author(s) -
Tetsuro Henta,
Yoshiyasu Itoh,
Miyuki Kobayashi,
Yoshiharu Ninomiya,
Akira Ishibashi
Publication year - 1999
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1999.02991.x
Subject(s) - medicine , photodynamic therapy , lesion , lymph node , etoposide , extramammary paget's disease , skin lesion , dermatology , chemotherapy , pathology , disease , surgery , chemistry , organic chemistry
A 74‐year‐old woman with extensive inoperable vulval extramammary Paget's disease who had lymph node and pulmonary metastases, was treated with etoposide (VP16) 100 mg and 5000 cGy electron beam irradiation, which reduced the lesion by 60%. Following these interventions, the residual lesion was successfully treated with repeated photodynamic therapy using δ‐aminolaevulinic acid, which achieved a nearly complete remission.