Premium
Microbiological and molecular diagnosis of deep localized cutaneous infection with Trichophyton mentagrophytes
Author(s) -
Sabine Sommer,
Richard Barton,
S. M. Wilkinson,
William Merchant,
E. G. V. Evans,
Martin Moore
Publication year - 1999
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1999.02985.x
Subject(s) - trichophyton , dermatophyte , itraconazole , trichophyton tonsurans , nail (fastener) , haeiii , medicine , dermatology , biology , microbiology and biotechnology , pathology , polymerase chain reaction , antifungal , genetics , restriction fragment length polymorphism , materials science , gene , metallurgy
We describe a healthy young woman with a localized deep dermal infection on the right side of the chest wall. It was caused by the dermatophyte Trichophyton mentagrophytes , and resolved after two pulses of oral itraconazole 200 mg twice daily for 1 week. As cultural and microscopic features did not enable a precise identification of the fungus, molecular investigation was undertaken. Patterns of Hae III restriction digests of genomic DNA from the culture matched those from Arthroderma incurvata and A. benhamiae , which is the teleomorph of T. mentagrophytes var. mentagrophytes .