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Lichenoid tissue reaction in porphyria cutanea tarda
Author(s) -
Daniel Creamer,
Jane McGregor,
John Mcfadden,
J.L.M. Hawk
Publication year - 1999
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1999.02932.x
Subject(s) - porphyria cutanea tarda , dermis , dermatology , medicine , porphyria , pathology , histology , erythema , photosensitivity , actinic keratoses , basal cell , materials science , optoelectronics
We report a patient presenting with lichenoid plaques on exposed skin who had the metabolic features of porphyria cutanea tarda (PCT). Histology of lesional skin demonstrated a lichenoid inflammatory cell infiltrate in the upper dermis, while direct immunofluorescence revealed immunoreactive colloid bodies. Monochromator irradiation testing demonstrated photosensitivity in the visible spectrum consistent with porphyria. Solar‐simulated irradiation induced a papular reaction with lichenoid histological changes. We propose that this atypical presentation of PCT may reflect a lichenoid tissue response to a porphyrin‐mediated photochemical reaction.