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Erosive mucosal lichen planus: response to topical treatment with tacrolimus
Author(s) -
Claudia Vente,
Kristian Reich,
Rainer Rupprecht,
Christine Neumann
Publication year - 1999
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1999.02672.x
Subject(s) - tacrolimus , medicine , dermatology , oral lichen planus , surgery , transplantation
Erosive mucosal lichen planus is a painful and disabling inflammatory skin disease that is highly resistant to topical treatment. We report on six patients with severe recalcitrant erosive mucosal lichen planus who benefited from topical application of tacrolimus ointment. After 4 weeks of treatment, complete resolution was observed in three cases, and substantial improvement was achieved in the other three patients. In these cases, prolonged treatment resulted either in further improvement or in complete healing. All patients reported rapid relief from pain and burning. No severe side‐effects were observed.