Premium
Hyperpigmentation due to topical calcipotriol and photochemotherapy in two psoriatic patients
Author(s) -
Regine Gläser,
Joachim Röwert,
Ulrich Mrowietz
Publication year - 1998
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1998.02334.x
Subject(s) - calcipotriol , dermatology , medicine , hyperpigmentation , psoriasis , puva therapy , ultraviolet therapy , ultraviolet a , melanosome , melanin , genetics , biology
The vitamin D 3 analogue calcipotriol (calcipotriene) is an effective topical treatment for psoriasis. In combination with other antipsoriatic agents, such as ultraviolet radiation, calcipotriol is reported to improve the overall efficacy of the treatment. Here we describe two patients treated with a combination treatment of calcipotriol and bath psoralens and ultraviolet A who developed hyperpigmentation at the lesional sites where calcipotriol ointment was applied.