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Erythropoietic protoporphyria improving during pregnancy
Author(s) -
Bewley Ap,
M. Keefe,
White Je
Publication year - 1998
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1998.02333.x
Subject(s) - erythropoietic protoporphyria , pregnancy , medicine , lactation , obstetrics , endocrinology , protoporphyrin , chemistry , biology , photochemistry , porphyrin , genetics
Erythropoietic protoporphyria is an uncommon disorder which causes a photosensitive cutaneous reaction, and occasionally hepatic dysfunction in affected individuals. We report a patient with erythropoietic protoporphyria who improved symptomatically during her two pregnancies. In the latter pregnancy, quantitative levels of plasma and erythrocyte protoporphyrins were reduced by more than half during the pregnancy compared with the levels before pregnancy and during lactation.