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Post‐kala‐azar dermal leishmaniasis with mucosal involvement in a kidney transplant recipient: treatment with liposomal amphotericin B
Author(s) -
Gastón Roustán,
José Alberto Rojas Jiménez,
B Gutiérrez-Solar,
Javier Gállego,
Jorge Alvar,
Mercedes Patrón
Publication year - 1998
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1998.02139.x
Subject(s) - amphotericin b , medicine , leishmaniasis , immunosuppression , visceral leishmaniasis , indian subcontinent , dermatology , cutaneous leishmaniasis , immunology , antifungal , ancient history , history
Post‐kala‐azar dermal leishmaniasis (PKDL) is a rare clinical variant of cutaneous leishmaniasis. It is very common in the Indian subcontinent and less frequent in East Africa, but exceptional in the American and European continents. We have observed a case of PKDL in a renal transplant recipient. No systemic symptoms were present. The patient was treated with liposomal amphotericin B. We emphasize the unusual aspects of this case: the appearance of PKDL in Europe, its relationship with immunosuppression, the severe mucosal involvement and the excellent response to liposomal amphotericin B, a newly described treatment for the disease.

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