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Dermatitis herpetiformis and bullous pemphigoid: a developing association confirmed by immunoelectronmicroscopy
Author(s) -
SETTERFIELD J.,
BHOGAL B.,
BLACK M.M.,
MCGIBBON D.H.
Publication year - 1997
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1997.d01-1181.x
Subject(s) - dermatitis herpetiformis , bullous pemphigoid , dermatology , medicine , pemphigoid , pathology , immunology , antibody , disease
Summary We report a case of dermatitis herpetiformis associated with bullous pemphigoid in which the clinical, histopathological and immunopathological findings were corroborated by direct immunoelectronmicroscopy performed on normal and peri–lesional skin biopsies. Western immunoblotting detected the 180kDa BPAG2 consistent with bullous pemphigoid. HLA–typing confirmed the DR3 DQ2 haplotype associated with dermatitis herpetiformis.