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Unusual skin ulceration in an HIV‐positive patient who had cutaneous syphilis and neurosyphilis
Author(s) -
TUCKER S.C,
YATES V.M,
THAMBAR I.V.
Publication year - 1997
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1997.01846.x
Subject(s) - neurosyphilis , syphilis , medicine , treponema , human immunodeficiency virus (hiv) , dermatology , presentation (obstetrics) , pathology , immunology , surgery
Summary We present a case of a patient coinfected with syphilis and the human immunodeficiency virus (HIV) who had unusual and severe cutaneous ulceration. The profound immune defects associated with HIV may lead to an altered clinical presentation and a more aggressive course in patients infected with Treponema pallidum. Despite non‐confirmatory histological findings, we feel our patient's cutaneous ulcers probably represent superficial gummata, which have failed to resolve completely following currently accepted high‐dose antisyphilis chemotherapy.