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Systemic involvement in scleredema of Buschke associated with IgG‐kappa paraproteinaemia
Author(s) -
BASARAB T.,
BURROWS N.P.,
MUNN S.E,
JONES R.RUSSELL
Publication year - 1997
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1997.01844.x
Subject(s) - medicine , mucinosis , mucin , systemic disease , pathology , histology , dermatology , bone marrow , salivary gland , immunopathology
Summary Scleredema is a rare primary cutaneous mucinosis. Systemic involvement is uncommon and histological confirmation is often lacking. We report a case of a 60‐year‐old man with scleredema and evidence of mucin deposition on biopsies from multiple extracutaneous sites. The bone marrow, nerve, hepatic and salivary gland involvement seen on histology in our patient has not, to our knowledge, been previously reported in this condition.