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Atypical eumycetoma caused by Phialophora parasitica successfully treated with itraconazole and flucytosine
Author(s) -
HOOD S.V.,
MOORE C.B.,
CHEESBROUGH J.S.,
MENE A.,
DENNING D.W.
Publication year - 1997
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1997.01834.x
Subject(s) - itraconazole , flucytosine , antifungal , medicine , mycosis , fungi imperfecti , dermatology , biology , microbiology and biotechnology , surgery , amphotericin b
Summary Phialophora species are occasional pathogens causing subcutaneous and invasive disease. We report the first case of eumycetoma caused by P. parasitica in an otherwise healthy U.K. resident who visited India. She failed to respond to surgical excision and itraconazole. 400 mg daily, but responded to itraconazole, 400 mg daily, and flucytosine, 1 g three times daily, lor 12 months. In vitro susceptibility testing predicted a response.