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Woody hands in a patient with pancreatic carcinoma: a variant of cancer‐associated fasciitis‐panniculitis syndrome
Author(s) -
COX N.H.,
RAMSAY B.,
DOBSON C.,
COMAISH J.S.
Publication year - 1996
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1996.d01-1110.x
Subject(s) - newcastle upon tyne , medicine , dermatology , pancreatic carcinoma , pancreatic cancer , cancer , history , art history
SUMMARY We report an elderly woman with rapidly progressive painless, woody induration ofthe hands. Mild diabetes mellitus was demonstrated. Skin biopsy features included broad fibrous bands extending deeply into subcutaneous fat, a mild mononuclear cell infiltrate, and post‐thrombolic recanalization of a deep vessel in one specimen. The patietU developed uncontrolled haematemcsis and was demonstrated at laparotomy to have disseminated pancreatic carcinoma. The unusual clinical features and lemporal relationship between the skin changes and the tumour suggesi a paraneo‐plastic eruption, whieh appears besl classified as an example of cancer‐associated fasciitis—panniculitis syndrome.