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Successful treatment with fluconazole of protothecosis developing at the site of an intralesional corticosteroid injection
Author(s) -
KIM S.T.,
SUH K.S.,
CHAE Y.S.,
KIM Y.J.
Publication year - 1996
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1996.d01-1084.x
Subject(s) - fluconazole , ketoconazole , triamcinolone acetonide , amphotericin b , medicine , dermatology , regimen , corticosteroid , surgery , antifungal
Summary We report a case of cutaneous protothecosis treated successfully with oral fluconazole. Fluconazole appears to be an effective alternative to conventional drugs for the treatment of cutaneous protothecosis. Cutaneous protothecosis is an uncommon infection due to achlorophyllic, saprophytic, algae‐like unicellular organisms of the genus Prototheca that occurs mainly in immunocompromised patients. To date there is no standard treatment regimen. Surgical excision, oral ketoconazole, intravenous amphotericin B alone or in combination with oral teracycline have been reported to be effective in the management of protothecosis. 1–3 We report a 55‐year‐old immunocompetent woman with cutaneous protothecosis which developed at the site of intralesional triamcinolone acetonide injection, who was successfully treated with oral fluconazole.