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Acrodermatitis chronica atrophicans in an 11‐year‐old girl
Author(s) -
MUELLEGGER R.R.,
SCHLUEPEN E.M.,
MILLNER M.M.,
SOYER H.P.,
VOLKENANDT M.,
KERL H.
Publication year - 1996
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1996.d01-1051.x
Subject(s) - acrodermatitis , lyme borreliosis , borrelia burgdorferi , ceftriaxone , dermatology , medicine , serology , borrelia burgdorferi infection , polymerase chain reaction , lyme disease , girl , pathology , immunology , biology , gene , microbiology and biotechnology , antibody , antibiotics , genetics , alternative medicine
Summary We report a case of acrodermatitis chronica atrophicans in an 11‐year‐old girl living in an area endemic for Lyme borreliosis. The diagnosis was first made on the basis of clinical, histopathological and serological findings. Moreover, Borrelia burgdorferi ‐specific DNA was amplified from lesional skin by polymerase chain reaction. Intravenous treatment with ceftriaxone (2g once daily) for 2 weeks was initiated. The skin changes clearly responded to the therapy, and Borrelia burgdorferi ‐specific gene segments were no longer detectable by polymerase chain reaction. This is the first report of molecular‐proven acrodermatitis chronica atrophicans in childhood. The occurrence of this late skin manifestation of Lyme borreliosis in children is reviewed.