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Cutaneous lymphocytic vasculitis in acute myeloid leukaemia
Author(s) -
FARRELL A.M.,
GOOPTU C.,
WOODROW D.,
COSTELLO C.,
BUNKER C.B.,
CREAM J.J.
Publication year - 1996
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1996.d01-1025.x
Subject(s) - medicine , vasculitis , polyarteritis nodosa , bone marrow , pathology , myeloid , biopsy , skin biopsy , dermatology , immunology , disease
Summary We report a 63‐year‐old woman who presented with an 8‐week history of widespread indurated, purpuric lesions associated with weight loss of 7 kg and several episodes of epistaxis. A skin biopsy demonstrated a lymphocytic vasculitis with haemorrhage and parakeratosis. A blood flim and bone marrow examination showed features of a myelodysplastic syndrome in transformation to acute myeloid leukaemia. Leucocytoclastic vasculitis and polyarteritis nodosa occur in association with acute myeloid leukaemia, but the association with lymphocytic vasculitis is new.