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Acute myelocytic leukaemia associated with Kaposi's sarcoma in a patient without serum antibodies to human immunodeficiency virus type 1
Author(s) -
HERNÁNDEZ D. E.,
PELLINO M. L.,
RAMÍREZ B.
Publication year - 1996
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1996.49765.x
Subject(s) - medicine , antibody , virology , human immunodeficiency virus (hiv) , sarcoma , myelocytic leukemia , virus , immunology , leukemia , pathology
Summary We report a 35‐year‐old man with acute myelocytic leukaemia and Kaposi's sarcoma, whose serum was non‐reactive for antibodies to human immunodeficiency virus type‐1 by enzyme‐linked immunosorbent assay. Western blot and immunofluorescence. Complete remission of both the acute leukaemia and the Kaposi's sarcoma followed treatment with mitoxantrone and cytosine arabinoside. We speculate that the rapid regression of the lesions of Kaposi's sarcoma might be related to mitoxantrone and to the return to normal of his peripheral helper and suppressor T‐cell counts.