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Physical mapping of CSF2RA , ANT3 and STS on the pseudoautosomal region of bovine chromosome X
Author(s) -
Moore S. S.,
Byrne K.,
Johnson S. E.,
Kata S.,
Womack J. E.
Publication year - 2001
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1046/j.1365-2052.2001.00740.x
Subject(s) - pseudoautosomal region , biology , genetics , radiation hybrid mapping , x chromosome , gene , microsatellite , gene mapping , y chromosome , genetic linkage , chromosome , genome , allele
The pseudoautosomal region (PAR) of bovine chromosome X (BTA X) has a particularly low representation of genes and markers, making comparative gene mapping in this region difficult. We describe the localization of three genes , colony‐stimulating factor 2 receptor alpha ( CSF2RA ), ADP/ATP translocase 3 ( ANT3 ) and steroid sulphatase ( STS ) on PAR of BTA X using a 5000 rad whole‐genome radiation hybrid panel. The relationship of these genes to a number of previously mapped simple sequence repeat (microsatellite) markers is determined by physical and radiation hybrid mapping methods. The resulting radiation hybrid map resolves a discrepancy between the two major bovine linkage maps in the PAR of BTA X.