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Mapping of calpastatin and three microsatellites to porcine chromosome 2q2·1‐q2·4
Author(s) -
Ernst C. W.,
Robic A.,
Yerle M.,
Wang L.,
Rothschild M. F.
Publication year - 1998
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1046/j.1365-2052.1998.00319.x
Subject(s) - microsatellite , biology , genetics , genetic linkage , calpastatin , gene mapping , chromosome , linkage (software) , gene , microbiology and biotechnology , allele , biochemistry , calpain , enzyme
Three polymorphisms were identified in a 1·6‐kb fragment of the porcine calpastatin (CAST) gene and these polymorphisms were used for genetic linkage mapping. Linkage analysis revealed significant linkage of CAST to five microsatellites previously mapped to porcine chromosome 2; these microsatellites were S0010, S0226, Sw14, Sw395 and Sw776. A somatic cell hybrid panel was used to determine the chromosomal localization of CAST and the microsatellites S0091, S0226 and Sw395. All of these were localized to the region 2q2·1–q2·4.