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The effect of normobaric hyperoxia on cardiac index in healthy awake volunteers
Author(s) -
Harten J. M.,
Anderson K. J.,
Angerson W. J.,
Booth M. G.,
Kinsella J.
Publication year - 2003
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1046/j.1365-2044.2003.03333.x
Subject(s) - medicine , cardiac index , heart rate , cardiac output , anesthesia , hemodynamics , cardiology , hyperoxia , blood pressure , mean arterial pressure , vascular resistance , lung
Summary Fifteen healthy volunteers were exposed to a stepwise increase in F I O 2 between 0.21 and 1.0, and their haemodynamic responses were measured with a non‐invasive transthoracic bio‐impedance monitor. There was mean reduction in cardiac index from 3.44 to 3.08 l.min −1 .m −2 (10.7%, p < 0.001). The mean reduction in heart rate was from 77.3 to 69.1 beats.min −1 (10.5%, p < 0.001) and the mean systemic vascular index increased from 2062 to 2221 dyne.s −1 .cm −5 .m −2 (7.7%, p < 0.025). There were no significant changes in stroke index or mean arterial pressure. These changes are similar quantitatively and qualitatively to those previously reported by dye dilution techniques.