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Caudal ropivacaine and ketamine for postoperative analgesia in children
Author(s) -
Lee H. M.,
Sanders G. M.
Publication year - 2000
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1046/j.1365-2044.2000.01330-2.x
Subject(s) - ropivacaine , medicine , ketamine , anesthesia , sedation , emergence delirium , nausea , vomiting , visual analogue scale , postoperative nausea and vomiting , surgery , sevoflurane
In a prospective, randomised, double‐blind clinical study, we studied 32 ASA grade I and II boys aged 18 months to 12 years, scheduled for circumcision under general anaesthesia on an outpatient basis. They were randomly allocated to one of two groups: those in the ropivacaine group received caudal ropivacaine 0.2% 1 ml.kg −1 for postoperative analgesia and those in the ketamine/ropivacaine group received caudal ropivacaine 0.2% 1 ml.kg −1 plus caudal ketamine 0.25 mg.kg −1 . Postoperative pain was assessed using a modified 10‐cm visual analogue scale and analgesia was administered if the pain score exceeded a value of 3. The median duration of analgesia was significantly longer in the ketamine/ropivacaine group (12 h) than in the ropivacaine group (3 h, p < 0.0001), and subjects in the ropivacaine group required significantly more doses of postoperative analgesia than those in the ketamine/ropivacaine group (p < 0.0001). There were no differences between the groups in the incidence of postoperative nausea, vomiting, sedation, emergence delirium, nightmares, hallucinations, motor block and urinary retention.