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Profound motor blockade with epidural ropivacaine following spinal bupivacaine
Author(s) -
Donal J. Buggy,
C. M. Allsager,
S. Coley
Publication year - 1999
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1046/j.1365-2044.1999.01006.x
Subject(s) - ropivacaine , medicine , bupivacaine , anesthesia , intrathecal , motor block , blockade , caesarean section , local anaesthetic , local anesthetic , epidural administration , pregnancy , receptor , biology , genetics
Ropivacaine, a relatively new amide local anaesthetic, reputedly produces less motor block than equivalent doses of bupivacaine, potentially combining high‐quality analgesia with the ability to ambulate. We report two cases of prolonged, profound motor block with patient‐controlled epidural analgesia using 0.1% ropivacaine, following spinal bupivacaine for Caesarean section. As there was no evidence of inadvertent intrathecal ropivacaine administration or of any neurological injury, we hypothesise that epidural ropivacaine may interact with intrathecal bupivacaine to prolong its effect.