Premium
Continuous propofol administration for suxamethonium‐induced postoperative myalgia
Author(s) -
Manataki A. D.,
Arnaoutoglou H. M.,
Tefa L. K.,
Glatzounis G. K.,
Papadopoulos G. S.
Publication year - 1999
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1046/j.1365-2044.1999.00753.x
Subject(s) - medicine , myalgia , propofol , isoflurane , anesthesia , creatine kinase
The effect of continuous propofol administration on creatine kinase and suxamethonium‐induced postoperative myalgia was evaluated in 50 patients randomised into two groups of 25 patients each. Induction of anaesthesia was identical in all patients. Anaesthesia was maintained with 66% nitrous oxide in oxygen supplemented by either isoflurane 1% or continuous propofol. Creatine kinase was measured before and after operation. Myalgia was evaluated postoperatively by a blinded observer. The median level of myalgia was reduced significantly in the continuous propofol group (p = 0.011). The median creatine kinase value increased significantly in the isoflurane group (from 90 to 160 IU, p = 0.001).