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Regular medication and paracetamol overdose
Author(s) -
Isbister G. K.,
Downes F.,
Whyte I. M.
Publication year - 2003
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1046/j.1365-2036.2003.01444.x
Subject(s) - medicine , referral , population , drug overdose , tertiary referral hospital , pediatrics , emergency medicine , poison control , retrospective cohort study , surgery , family medicine , environmental health
Sirs, We noticed the analysis by Schmidt and Dalhoff of the effect of regular medication on the outcome of paracetamol poisoning. There are a number of methodological problems in the design of the study and difficulties with the presentation of the results that make the conclusions and interpretation less reliable than stated. There is, in fact, little evidence to support the observation that opioid analgesics have an effect on paracetamol poisoning.