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Low‐salt bowel cleansing preparation (LoSo Prep) as preparation for colonoscopy: a pilot study
Author(s) -
Verghese V. J.,
Ayub K.,
Qureshi W.,
Taupo T.,
Graham D. Y.
Publication year - 2002
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1046/j.1365-2036.2002.01295.x
Subject(s) - bisacodyl , medicine , colonoscopy , bowel preparation , cathartic , suppository , gastroenterology , surgery , colorectal cancer , pharmacology , cancer
Summary Background : Currently available colon cleansing preparations are often poorly tolerated. Aim : To evaluate the efficacy of a low‐volume, low‐salt preparation for colonoscopy. Methods : This was a pilot study in patients scheduled for colonoscopy. The preparation consisted of 34 g of magnesium citrate and four bisacodyl tablets the day before the procedure, and one bisacodyl suppository on the morning of the procedure. Results : Twenty patients (age range, 49–81 years; all males) were entered into the study. There were no significant side‐effects associated with the preparation. All rated the taste as ‘tolerable or better’. The examination was considered to be adequate, with no limitations, in 17 patients (85%), and was scored as good to excellent (no solid stool) in 11 (55%), acceptable (small amounts of solid stool) in six (30%) and poor in three (15%: two in‐patients and one out‐patient). Importantly, two of the failures then received a standard polyethylene glycol preparation and again failed to show adequate colon preparation. Conclusions : This pilot study showed that the low‐salt colon cleansing preparation was an effective alternative preparation for colonoscopy.