Open AccessDeciphering host resistance and pathogen virulence: the Arabidopsis / Pseudomonas interaction as a model
Author(s) -
Quirino Betania F.,
Bent Andrew F.
Publication year - 2003
Publication title -
molecular plant pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 103
eISSN - 1364-3703
pISSN - 1464-6722
DOI - 10.1046/j.1364-3703.2003.00198.x
Subject(s) - pseudomonas syringae , biology , virulence , arabidopsis , effector , pathogen , arabidopsis thaliana , computational biology , gene , genetics , genome , plant disease resistance , gene expression profiling , microbiology and biotechnology , gene expression , mutant
SUMMARY The last decade has witnessed steady progress in deciphering the molecular basis of plant disease resistance and pathogen virulence. Although contributions have been made using many different plant and pathogen species, studies of the interactions between Arabidopsis thaliana and Pseudomonas syringae have yielded a particularly significant body of information. The present review focuses on recent findings regarding R gene products and the guard hypothesis, RAR1/SGT1 and other examples where protein processing activity is implicated in disease resistance or susceptibility, the use of microarray expression profiling to generate information and experimental leads, and important molecular‐ and genome‐level discoveries regarding P. syringae effectors that mediate bacterial virulence. The development of the Arabidopsis – Pseudomonas model system is also reviewed briefly, and we close with a discussion of characteristics to consider when selecting other pathosystems as experimentally tractable models for future research.