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Transmission of Helicobacter pylori infection in families of preschool‐aged children from Minas Gerais, Brazil
Author(s) -
Rocha Gifone Aguiar,
Rocha Andreia Maria Camargos,
Silva Luciana Diniz,
Santos Adriana,
Bocewicz Ana Carolina Dias,
Queiroz Renata de Magalhães,
Bethony Jeffrey,
Gazzinelli Andréa,
CorrêaOliveira Rodrigo,
Queiroz Dulciene Maria Magalhães
Publication year - 2003
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1046/j.1360-2276.2003.01121.x
Subject(s) - odds ratio , medicine , demography , confidence interval , offspring , helicobacter pylori , logistic regression , transmission (telecommunications) , risk factor , pregnancy , biology , sociology , electrical engineering , genetics , engineering
Summary We evaluated the role of the family in the transmission of Helicobacter pylori infection in preschool‐aged children from a rural district in the State of Minas Gerais, Brazil. Sixty‐six families (66 index children, 63 mothers, 60 fathers and 134 siblings), defined as at least one parent living in the same household with at least one offspring up to 8 years old, were studied. Odds ratios (OR) and 95% confidence intervals (CI) were estimated by logistic regression controlling for age, gender, number of children in household and H. pylori status of the father, mother and siblings. The prevalence of the infection was 69.7% (469 of 673) and it increased with age ( P < 0.001). Positive mothers were a strong and independent risk factor for infection (OR 22.70; 95% CI 2.31–223.21). Positive siblings were also positively associated with infection (OR 1.81; 95% CI 1.01–3.30).