Premium
Acetic acid and 3‐hydroxybutyric acid levels in cerebrospinal fluid of cattle
Author(s) -
SATO Hiroshi,
KUROSAWA Takashi,
OIKAWA Shin
Publication year - 2002
Publication title -
animal science journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 38
eISSN - 1740-0929
pISSN - 1344-3941
DOI - 10.1046/j.1344-3941.2002.t01-1-00020.x
Subject(s) - cerebrospinal fluid , acetic acid , medicine , endocrinology , chemistry , blood plasma , population , biology , biochemistry , environmental health
To evaluate the importance of acetic acid and 3‐hydroxybutyric acid (3‐HB) in cerebrospinal fluid (CSF) of cattle, CSF samples were taken from a population of 60 cattle including healthy and sick animals with central nervous disorders. Mean acetic acid and 3‐HB levels in blood plasma were 0.30 (SD 0.24) and 0.30 (SD 0.28) mM, and those in CSF were 0.14 (SD 0.06) and 0.08 (SD 0.07) mM, respectively. Significant differences were observed between plasma and CSF samples for both acetic acid and 3‐HB levels. Acetic acid levels in CSF showed less relationship with those in blood plasma, whereas plasma 3‐HB levels accompanied proportional changes with its CSF levels, which were about 30% of plasma 3‐HB. It was revealed that both acetic acid and 3‐HB levels in plasma and CSF have less relationship to glucose levels in plasma and CSF; therefore, the decrease of glucose levels in plasma or CSF is not necessarily accompanied by hyperketonemia.