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Iron status in anemic pregnant women
Author(s) -
Thinkhamrop Jadsada,
Apiwantanakul Somnuk,
Lumbiga Pisake,
Buppasiri Pranom
Publication year - 2003
Publication title -
journal of obstetrics and gynaecology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.597
H-Index - 50
eISSN - 1447-0756
pISSN - 1341-8076
DOI - 10.1046/j.1341-8076.2003.00094.x
Subject(s) - medicine , iron deficiency , hemoglobin , hemoglobinopathy , anemia , ferritin , thalassemia , iron deficiency anemia , pediatrics , obstetrics , disease
Aim: A descriptive study at a tertiary care center was carried out to assess the prevalence of iron status in anemic pregnant women and to determine the appropriate iron supplement. Methods: Eligible subjects were pregnant women with a hemoglobin concentration <11 g/dL. Pregnant women who received antenatal vitamin and/or iron supplements before blood testing and women with an underlying chronic disease were excluded. Hemoglobinopathy was defined by hemoglobin typing other than HbA 2 A, percentage of HbA 2 >4%, and HbF >1.1%. We diagnosed iron deficiency and iron depletion if their serum ferritin were <12 and 20 ng/mL, respectively, whereas anemia from undetermined causes was defined by hemoglobin typing, namely: A 2 A, HbA 2 <4% and HbF <1.1%, and serum ferritin>20 ng/mL. Results: Among the 137 anemic pregnant women recruited, 67 (49.8%) had HbA 2 A, 47 (34.3%) HbEA, 15 (10.9%) HbEE, 3 (2.2%) HbCSA 2 A, 2 (1.5%) HbCSEA, 1 (0.7%) HbCSA 2 A Bart’s, 1 (0.7%) HbEA Bart’s, and 1 (0.7%) β‐thalassemia. Among the 67 women with normal hemoglobin (HbA 2 A), 14 (20.9%) had iron deficiency, and 12 (17.9%) iron depletion. Among the 70 women with hemoglobinopathy, 6 (8.6%) had iron deficiency, and 10 (14.3%) iron depletion. Conclusions: Anemic pregnant women with hemoglobinopathy could also be iron deficient so will need iron supplementation, as other pregnant women do, and some iron replacement therapy.