Premium
MsqTc3, a Tc3 ‐like transposon in the yellow fever mosquito Aedes aegypti
Author(s) -
Shao Hongguang,
Qi Yumin,
Tu Zhijian
Publication year - 2001
Publication title -
insect molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.955
H-Index - 93
eISSN - 1365-2583
pISSN - 0962-1075
DOI - 10.1046/j.0962-1075.2001.00280.x
Subject(s) - aedes aegypti , transposable element , biology , open reading frame , genetics , inverted repeat , aedes , caenorhabditis elegans , genome , virology , gene , peptide sequence , botany , dengue fever , larva
A novel transposon, MsqTc3‐Aa , has been discovered in the yellow fever mosquito, Aedes aegypti . Evidence of its past mobility is presented. There are approximately 100 copies of MsqTc3‐Aa in A. aegypt i, eight of which have been isolated and sequenced. All sequenced copies are more than 99% identical to their consensus, indicating recent mobilization. The MsqTc3‐Aa consensus contains imperfect terminal inverted repeats (TIRs) and an open reading frame (ORF) interrupted by an intron. Sequence, structural and phylogenetic analysis showed that MsqTc3‐Aa is a distant relative of Tc3 , an active transposon in Caenorhabditis elegans . These results may provide useful information for the current effort to control mosquito‐borne diseases using genetic approaches.