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Twin chorionicity and pre‐eclampsia
Author(s) -
Savvidou M. D.,
Karanastasi E.,
Skentou C.,
Geerts L.,
Nicolaides K. H.
Publication year - 2001
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.0960-7692.2001.00470.x
Subject(s) - medicine , obstetrics , eclampsia , odds ratio , incidence (geometry) , obstetrics and gynaecology , twin pregnancy , gestation , gynecology , twin to twin transfusion syndrome , monochorionic twins , pregnancy , gestational age , confidence interval , genetics , physics , optics , biology , pathology
Objective To determine whether the incidence of pre‐eclampsia is different in dichorionic compared to monochorionic twin pregnancies. Methods The study involved 666 twin pregnancies resulting in two live births after 24 weeks of gestation. Ultrasound examination at 10–14 weeks of gestation demonstrated that 171 (25.7%) were monochorionic and 495 (74.3%) were dichorionic twins. Pregnancy outcome information regarding the development of pre‐eclampsia was obtained from the maternity units. The incidence of pre‐eclampsia in the dichorionic and monochorionic twin pregnancies was compared. Results The incidence of pre‐eclampsia in monochorionic twin pregnancies (9.4%) was not significantly different from that in dichorionic pregnancies (7.3%) ( P = 0.48). Multiple logistic regression revealed that chorionicity has no effect on the development of pre‐eclampsia after adjusting for maternal age, ethnic group, maternal smoking, parity and gestational age at delivery ( P = 0.6; odds ratio for monochorionic compared with dichorionic twin pregnancies, 1.19; 95% confidence interval, 0.61–2.3). Conclusion In twin pregnancies chorionicity does not affect the incidence of pre‐eclampsia. Copyright © 2001 International Society of Ultrasound in Obstetrics and Gynecology