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Development of an in vitro efficacy test for self‐tanning formulations
Author(s) -
Jermann R.,
Toumiat M.,
Imfeld D.
Publication year - 2002
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1046/j.0412-5463.2001.00123.x
Subject(s) - sunbathing , sunscreening agents , in vitro , human skin , chemistry , in vivo , dermatology , medicine , biology , microbiology and biotechnology , skin cancer , biochemistry , cancer , genetics
Synopsis In the last few years, the desire to acquire a tan without sunbathing has grown. In response, many cosmetic companies have produced self‐tanning preparations. However, to optimize these formulations, a suitable model to assess the colour induced on the skin remains to be developed. We have developed an in vitro method using a synthetic skin in order to study the efficacy of self‐tanning formulations. The in vitro test was then used to study the influence of cosmetic ingredients upon the colour induced by erythrulose‐ or dihydroxyacetone‐containing formulations. Finally, an in vivo study allowed us to relate the results obtained in vitro with those found on human skin. The results show that this in vitro test system is a reliable tool to predict the efficacy of self‐tanning products.