Open AccessProteolytic systems of archaea: slicing, dicing, and mincing in the extreme
Author(s) -
Julie A. MaupinFurlow
Publication year - 2018
Publication title -
emerging topics in life sciences
Language(s) - English
Resource type - Journals
eISSN - 2397-8562
pISSN - 2397-8554
DOI - 10.1042/etls20180025
Subject(s) - proteolysis , proteases , archaea , biochemistry , aaa proteins , deubiquitinating enzyme , protease , proteasome , ubiquitins , atpase , biology , ubiquitin , chemistry , microbiology and biotechnology , enzyme , ubiquitin ligase , gene
Archaea are phylogenetically distinct from bacteria, and some of their proteolytic systems reflect this distinction. Here, the current knowledge of archaeal proteolysis is reviewed as it relates to protein metabolism, protein homeostasis, and cellular regulation including targeted proteolysis by proteasomes associated with AAA-ATPase networks and ubiquitin-like modification. Proteases and peptidases that facilitate the recycling of peptides to amino acids as well as membrane-associated and integral membrane proteases are also reviewed.