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Protein balance: a fundamental question of cell biology needing reappraisal
Author(s) -
Wheatley Denys N
Publication year - 2011
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1042/cbi20110067
Subject(s) - balance (ability) , mechanism (biology) , microbiology and biotechnology , biology , work (physics) , computational biology , neuroscience , engineering , epistemology , mechanical engineering , philosophy
Although protein synthesis and protein degradation are two independent processes that are firmly regulated, how they maintain a balance of protein in the non‐growing cell remains to be established. In work in the 1980s, the author suggested a self‐regulating mechanism. However, experimental work on this interesting and fundamental problem is needed for a better understanding of ‘protein balance’ in cells.