Irrelevance of USF2 rs916145 polymorphism with the risk of biliary atresia susceptibility in Southern Chinese children | Zendy

Lei Chen | Zendy; Ming Fu | Zendy; Ledong Tan | Zendy; Jinglu Zhao | Zendy; Xiaogang Xu | Zendy; Yuzhen Lin | Zendy; Qian Zhong | Zendy; Ruisui Zhong | Zendy; Ruizhong Zhang | Zendy; Jixiao Zeng | Zendy

Open Access

Irrelevance of USF2 rs916145 polymorphism with the risk of biliary atresia susceptibility in Southern Chinese children

Author(s) -

Lei Chen,

Ming Fu,

Ledong Tan,

Jinglu Zhao,

Xiaogang Xu,

Yuzhen Lin,

Qian Zhong,

Ruisui Zhong,

Ruizhong Zhang,

Jixiao Zeng

Publication year - 2020

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20193623

Subject(s) - odds ratio , genotype , gastroenterology , biliary atresia , confidence interval , etiology , polymorphism (computer science) , medicine , pathogenesis , genetics , biology , gene , transplantation , liver transplantation

Biliary atresia (BA) is a very rare neonatal disease, however, it has been the most common cause of obstructive jaundice in infancy. The complex pathogenesis of BA is not entirely clear and a lot of possible pathogenic mechanisms have been proposed to explain the etiology of BA, including genetic, inflammatory, environmental and developmental abnormalities. As a transcription factor, USF2 gene rs916145 polymorphism has been shown to be related to the risk of BA.

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